If Luisa says "nose" out of the blue, it means that she wants someone to get a handkerchief and blow her nose (or give her one, so she can do it herself).
The other day, I was home alone with her, and I had to go to the toilet. Seconds after I sat down, she called from her room: "Nose." I called to her and told her to come to where I was and I would give her a piece of toilet paper to wipe her nose. She came running, but when I held out some toilet paper to her, she shook her head, took the toilet paper, and went back to her room. (I had just enough time to notice that her nose was not running.)
I was quickly done on the toilet, and a few moments later I went into her room. She was standing by the couch, holding the toilet paper I had given her, and blowing the nose of the first wild thing in "Where the Wild Things Are," which is a sea monster that is exhaling a whole cloud of vapor (like a whale)!