A Ground-Up Millipede

Thomas Willis was a 17th-century English doctor who, among other things, coined the term "neurology" and collaborated with Christopher Wren (who did the drawings) to produce the first accurate description of the structures of the human brain. The story of Willis's research and medical practice is told in Carl Zimmer's book Soul Made Flesh: The Discovery of the Brain ... (there's more to its title, but it's just marketing ...).

Zimmer talks a great deal about the historical context of seventeenth-century England, not just to add color but because Willis's biography (like that of anyone living through it) was strongly influenced by the English Civil War. After the Restoration and the Great Fire of London, Willis moved his practice from Oxford to London and became the most famous physician in England (in part because of his work with Wren describing the brain). Zimmer writes of his medical practice as follows:

His theories about how people became sick and how the body worked were hugely popular. Yet his remedies remained, as ever, generally useless. He continued prescribing his eclectic blend of medicines—a blistering plaster for one patient, a ground-up millipede for another—and claimed success when his patients recovered and escaped blame when they didn't. If they recuperated, they usually did so in spite of his attentions.

The popularity of a medical treatment bears no necessary relationship to its effectiveness. Its popularity might well be based on other things—in this case, the fame of Willis's research—or on logical fallacies, such as the clear post hoc, ergo proper hoc moment in the above passage. Perhaps ground-up millipedes are good for something, but no matter how much he had discovered about the structure of the brain, Willis was probably just making it up when he decided that millipedes would do the job.

Germ Theory

It's hard for me to wrap my head around the idea that there might be people out there—doctors, even!—who dispute the germ theory of disease. But there are, and some of them are trying to provide medical treatment to terminally ill patients (and anyone else they can convince to put themselves into their hands), as is shown by this post about such a case.

David Gorski writes of the era when the germ theory was first developed:

Béchamp, as you may remember, was a contemporary of Louis Pasteur and proposed a competing hypothesis for the cause of infectious disease, which he dubbed the pleomorphic theory. The concept he championed was that bacteria do not cause disease but are rather a manifestation of disease. In other words, diseased tissues produce bacteria, arising from structures that Béchamp called microzymas, which to him referred to a class of enzyme. Béchamp postulated that microzymas are normally present in tissues and that their effects depended upon the cellular terrain. Of course, as we all know, ultimately Pasteur’s ideas won out based on evidence, experimentation, and clinical observation, relegating Béchamp to more or less a historical footnote. In fairness, it should be remembered that, 150 year ago, it wasn’t entirely clear who was correct, Pasteur or Béchamp. Given the technology and tools of the time, it was not a trivial matter to determine where bacteria arose, although it didn’t take long before experiments and methodology were developed that pretty much put Béchamp’s concepts to bed for good.

The point is well taken: when Pasteur was first developing his ideas, there were many other ideas in the air, and his ideas "won out" not because of some conspiracy to make them win out, but because they fit the evidence best.

If you're looking for an "alternative" doctor, at least try to find one who does not dismiss the germ theory and claim, among other things, that HIV "is not a virus but an alkaline antibody to buffer acid or antigens."

I'm not sure what I'll do when somebody comes along and says, "But Pasteur was wrong!"